This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
预测分子量
65 kDa
纯化方式
Affinity Purification
标记类型
Un-conjugated
克隆性
Monoclonal
来源
Rabbit
免疫源
A synthetic peptide of human SPAK
实际分子量
60 kDa
产品别名
DCHT; PASK; SPAK
货号: RMA02482
SPAK Recombinant Rabbit mAb
应用:
FCIHCWB
反应种属:
Human
¥ 1280
/ 50ul
库存充足
50ul100ul
产品详情
产品特性
应用
FCIHCWB
Uniprot
Q9UEW8
GeneID
27347
Isotype
IgG
反应种属
Human
Background
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]