Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Calculated molecular weight
77 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Monoclonal
Host species
Rabbit
Immunogen
A synthetic peptide of human DBF4
Observed molecular weight
77 kDa
Alias
ASK; CHIF; DBF4A; ZDBF1
Cat Number: RMA01280
DBF4 Recombinant Rabbit mAb
Applications:
WB
Species Reactivity:
Human
$ 229
/ 50ul
In Stock
50ul100ul
Description
Product Features
Applications
WB
Uniprot
Q9UBU7
GeneID
10926
Isotype
IgG
Species Reactivity
Human
Background
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.