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Phospho-MSK1 (Ser360) Rabbit pAb
Cat Number: DPA05700
Phospho-MSK1 (Ser360) Rabbit pAb
Applications:
ICC/IFIPWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
ICC/IFIPWB
Uniprot
O75582
GeneID
9252
Isotype
IgG
Calculated molecular weight
90 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Ser360 of human MSK1
Modification
Phospho-MSK1 (Ser360)
Observed molecular weight
90 kDa
Background
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.
Species Reactivity
HumanMouseRat
Alias
MSK1; RLPK; MSPK1
Cat Number: DPA05700
Phospho-MSK1 (Ser360) Rabbit pAb
Applications:
ICC/IFIPWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
ICC/IFIPWB
Uniprot
O75582
GeneID
9252
Isotype
IgG
Calculated molecular weight
90 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Ser360 of human MSK1
Modification
Phospho-MSK1 (Ser360)
Observed molecular weight
90 kDa
Background
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.
Species Reactivity
HumanMouseRat
Alias
MSK1; RLPK; MSPK1
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