The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
Calculated molecular weight
75 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser158 of human MARCKS
Modification
Phospho-MARCKS (Ser158)
Observed molecular weight
32 kDa
Alias
MACS; 80K-L; PKCSL; PRKCSL
Cat Number: DPA05529
Phospho-MARCKS (Ser158) Rabbit pAb
Applications:
WB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
WB
Species Reactivity
HumanMouseRat
Uniprot
P29966
GeneID
4082
Isotype
IgG
Background
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
Calculated molecular weight
75 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser158 of human MARCKS