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Phospho-STAT6 (Tyr641) Rabbit pAb
Cat Number: DPA05422
Phospho-STAT6 (Tyr641) Rabbit pAb
Applications:
FCIHCIPWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIHCIPWB
Uniprot
P42226
GeneID
6778
Isotype
IgG
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Calculated molecular weight
110 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Modification
Phospho-STAT6 (Tyr641)
Observed molecular weight
94 kDa
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr641 of human STAT6
Species Reactivity
HumanMouseRat
Alias
STAT6B; STAT6C; D12S1644; IL-4-STAT
Cat Number: DPA05422
Phospho-STAT6 (Tyr641) Rabbit pAb
Applications:
FCIHCIPWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIHCIPWB
Uniprot
P42226
GeneID
6778
Isotype
IgG
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Calculated molecular weight
110 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Modification
Phospho-STAT6 (Tyr641)
Observed molecular weight
94 kDa
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr641 of human STAT6
Species Reactivity
HumanMouseRat
Alias
STAT6B; STAT6C; D12S1644; IL-4-STAT
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