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TGF beta Receptor II Rabbit pAb
Cat Number: DPA01620
TGF beta Receptor II Rabbit pAb
Species Reactivity:
Human
Applications:
FCICC/IF
$ 169
/ 50μl
In Stock
50μl100μl
Description
Recommended Dilution
Product Features
Species Reactivity
Human
Applications
FCICC/IF
Purification method
Affinity Purification
Immunogen
Recombinant protein of human TGF beta Receptor II
Host species
Rabbit
Clonality
Polyclonal
Background
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Calculated molecular weight
65 kDa
GeneID
7048
Uniprot
P37173
Isotype
IgG
MW
85 kDa
Conjugate
Un-conjugated
Alias
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
Cat Number: DPA01620
TGF beta Receptor II Rabbit pAb
Species Reactivity:
Human
Applications:
FCICC/IF
$ 169
/ 50μl
In Stock
50μl100μl
Description
Recommended Dilution
Product Features
Species Reactivity
Human
Applications
FCICC/IF
Purification method
Affinity Purification
Immunogen
Recombinant protein of human TGF beta Receptor II
Host species
Rabbit
Clonality
Polyclonal
Background
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Calculated molecular weight
65 kDa
GeneID
7048
Uniprot
P37173
Isotype
IgG
MW
85 kDa
Conjugate
Un-conjugated
Alias
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; TGFbeta-RII
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