The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Calculated molecular weight
71 kDa
MW
71 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Polyclonal
Host species
Rabbit
Immunogen
A synthetic peptide of human Lamin B Receptor
Alias
PHA; LMN2R; TDRD18; DHCR14B
Cat Number: DPA01299
Lamin B Receptor Rabbit pAb
Applications:
FCICC/IFIHCIPWB
Species Reactivity:
HumanRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCICC/IFIHCIPWB
Species Reactivity
HumanRat
Uniprot
Q14739
GeneID
3930
Isotype
IgG
Background
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]