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SCP2 mouse monoclonal antibody, clone OTI1E4 (formerly 1E4)
Cat Number: GAM618358
SCP2 mouse monoclonal antibody, clone OTI1E4 (formerly 1E4)
Applications:
IHCWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
IHCWB
Uniprot
P22307
Isotype
IgG1
Background
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]
Calculated molecular weight
58.8 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human SCP2(NP_002970) produced in HEK293T cell.
Clone name
OTI1E4
Species Reactivity
HumanMouseRat
Alias
SCP2
Cat Number: GAM618358
SCP2 mouse monoclonal antibody, clone OTI1E4 (formerly 1E4)
Applications:
IHCWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
IHCWB
Uniprot
P22307
Isotype
IgG1
Background
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]
Calculated molecular weight
58.8 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human SCP2(NP_002970) produced in HEK293T cell.
Clone name
OTI1E4
Species Reactivity
HumanMouseRat
Alias
SCP2
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