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PHF7 mouse monoclonal antibody, clone OTI1G9 (formerly 1G9)
Cat Number: GAM616226
PHF7 mouse monoclonal antibody, clone OTI1G9 (formerly 1G9)
Applications:
FCIFIHCWB
Species Reactivity:
Human
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIFIHCWB
Uniprot
Q9BWX1
Isotype
IgG1
Species Reactivity
Human
Background
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]
Calculated molecular weight
43.6 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 155-381 of human PHF7(NP_057567) produced in E.coli.
Clone name
OTI1G9
Alias
PHF7
Cat Number: GAM616226
PHF7 mouse monoclonal antibody, clone OTI1G9 (formerly 1G9)
Applications:
FCIFIHCWB
Species Reactivity:
Human
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIFIHCWB
Uniprot
Q9BWX1
Isotype
IgG1
Species Reactivity
Human
Background
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]
Calculated molecular weight
43.6 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 155-381 of human PHF7(NP_057567) produced in E.coli.
Clone name
OTI1G9
Alias
PHF7
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