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SERPINB6 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
Cat Number: GAM615166
SERPINB6 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
Applications:
IHCWB
Species Reactivity:
Human
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
IHCWB
Uniprot
P35237
Isotype
IgG2a
Species Reactivity
Human
Background
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
Clone name
OTI2F8
Alias
SERPINB6
Cat Number: GAM615166
SERPINB6 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
Applications:
IHCWB
Species Reactivity:
Human
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
IHCWB
Uniprot
P35237
Isotype
IgG2a
Species Reactivity
Human
Background
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
Clone name
OTI2F8
Alias
SERPINB6
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