The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
预测分子量
104.3 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human ERCC4(NP_005227) produced in HEK293T cell.
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
预测分子量
104.3 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human ERCC4(NP_005227) produced in HEK293T cell.