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BEST3 (Bestrophin 3) mouse monoclonal antibody, clone OTI2H3 (formerly 2H3)
Cat Number: GAM613090
BEST3 (Bestrophin 3) mouse monoclonal antibody, clone OTI2H3 (formerly 2H3)
Applications:
FCIFWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIFWB
Uniprot
Q8N1M1
Isotype
IgG1
Background
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). [supplied by OMIM]
Calculated molecular weight
50.8 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
Clone name
OTI2H3
Species Reactivity
HumanMouseRat
Alias
BEST3
Cat Number: GAM613090
BEST3 (Bestrophin 3) mouse monoclonal antibody, clone OTI2H3 (formerly 2H3)
Applications:
FCIFWB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
FCIFWB
Uniprot
Q8N1M1
Isotype
IgG1
Background
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). [supplied by OMIM]
Calculated molecular weight
50.8 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
Clone name
OTI2H3
Species Reactivity
HumanMouseRat
Alias
BEST3
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