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Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2)
货号: GAM612077
Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2)
应用:
IF, IHC, WB
反应种属:
Human
¥ 960
/ 50ul
库存充足
50ul100ul
产品详情
推荐稀释比
产品特性
应用
IF, IHC, WB
Uniprot
P51580
纯化方式
Affinity Purification
克隆性
Monoclonal
反应种属
Human
来源
Mouse
Isotype
IgG1
免疫源
Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell.
预测分子量
28.2 kDa
Background
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
克隆号
OTI2A2
产品别名
TPMT
货号: GAM612077
Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2)
应用:
IF, IHC, WB
反应种属:
Human
¥ 960
/ 50ul
库存充足
50ul100ul
产品详情
推荐稀释比
产品特性
应用
IF, IHC, WB
Uniprot
P51580
纯化方式
Affinity Purification
克隆性
Monoclonal
反应种属
Human
来源
Mouse
Isotype
IgG1
免疫源
Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell.
预测分子量
28.2 kDa
Background
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
克隆号
OTI2A2
产品别名
TPMT
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