The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Calculated molecular weight
107.1 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 529-941 of human ERAP1 (NP_001035548) produced in E.coli.
Clone name
OTI7G4
Alias
ERAP1
Cat Number: GAM923999
ERAP1 mouse monoclonal antibody,clone OTI7G4
Applications:
WB
Species Reactivity:
HumanMouseRat
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
WB
Species Reactivity
HumanMouseRat
Uniprot
Q9NZ08
Isotype
IgG1
Background
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Calculated molecular weight
107.1 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 529-941 of human ERAP1 (NP_001035548) produced in E.coli.