E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA. [UniProtKB/Swiss-Prot Function]
Calculated molecular weight
81.3 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 311-554 of human TRIM56(NP_112223) produced in E.coli.
Clone name
OTI8E12
Alias
TRIM56
Cat Number: GAM920045
TRIM56 mouse monoclonal antibody,clone OTI8E12
Applications:
IHCWB
Species Reactivity:
Human
$ 169
/ 50ul
In Stock
50ul100ul
Description
Recommended Dilution
Product Features
Applications
IHCWB
Uniprot
Q9BRZ2
Isotype
IgG1
Species Reactivity
Human
Background
E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA. [UniProtKB/Swiss-Prot Function]
Calculated molecular weight
81.3 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 311-554 of human TRIM56(NP_112223) produced in E.coli.